What the science (and your body) actually need to age better.

At De Leon Precision Medicine, we help patients use nutrition and lifestyle as therapeutic tools—not just trends. One of the most talked-about strategies in longevity science today is fasting. But with so many versions—intermittent, prolonged, time-restricted—how do you know what actually supports your healthspan?

Let’s break it down.

First, What Is “Longevity” Medicine?

Longevity isn’t just about living longer. It’s about living better—with energy, mental clarity, and resilience well into your later decades.

Fasting and time-restricted eating (TRE) are practices that may support longevity by:

• Reducing chronic inflammation
• Supporting cellular repair (autophagy)
• Balancing blood sugar and insulin sensitivity
• Supporting mitochondrial health (your cellular energy centers)
• Promoting metabolic flexibility

Types of Fasting You Should Know

1. Time-Restricted Eating (TRE)
You eat within a specific window (e.g., 8–10 hours) each day. The most common format is 16:8 (16 hours fasting, 8 hours eating).

2. Intermittent Fasting (IF)
You alternate between eating and fasting across different days (e.g., 5:2 method, where you eat normally 5 days, fast 2 days).

3. Prolonged Fasting
Typically 24–72 hours. This should be done only under medical supervision and is not appropriate for everyone.

Fasting Benefits Backed by Research

Done correctly, fasting may promote:

• Cellular Repair (Autophagy): Helps clear damaged cells and rejuvenate tissues
• Hormone Regulation: Including insulin, leptin, and even growth hormone
• Gut Health Reset: Supports the gut lining and balances microbiome diversity
• Brain Health: Supports mental clarity and may reduce risk of cognitive decline
• Metabolic Resilience: Trains your body to burn fat efficiently without crashing

But not every body responds the same way—and that’s where personalized care matters.

When Fasting Can Backfire

At De Leon Precision Medicine, we see patients who’ve tried fasting and ended up with:

• Increased fatigue or brain fog
• Hormone disruptions (especially in women)
• Trouble sleeping or cortisol dysregulation
• Blood sugar crashes
• Muscle loss (especially without protein timing)

Fasting can be powerful—but not everyone benefits from the same protocol.

Who Might Benefit from Time-Restricted Eating?

Time-restricted eating is often a good starting point for:

• Those with mild insulin resistance or weight plateau
• Patients with busy schedules who prefer structure
• Individuals looking to lower inflammation
• Those seeking sustainable metabolic and hormone support

We often pair TRE with functional lab testing, nutritional guidance, and peptide or supplement support to maximize results.

Fasting isn’t a magic fix—but it can be a powerful lever for longevity.
The key is making sure your approach supports your biology—not works against it.

At De Leon Precision Medicine, we personalize nutrition and fasting strategies to your goals, labs, hormones, and lifestyle.

Curious if fasting is right for you? Let’s find out together.
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